Probably not the type of reference you were thinking about regarding reprogramming and impact on aging issues but I suspect it’s in the area you were thinking. I’m pretty sure it’s been mentioned here on LW before in other posts/comments. Interesting idea but implementation is problematic to say the least—but really hoping someone can figure it out.
Since a lot of this is way beyond my skill sets and knowledge, when you’re looking at the dynamic interplay aspect, is that purely internal to the cell or do you also look at the extra-cellular “communications”? If so, are you familiar with the Conboy’s plasma dilution experiments?
I’m not sure I’m understanding your claim here. I don’t think you’re suggesting a “if you build it they will come” type result from being in a dominant position. But I also don’t quite get why being in a dominant position in one space has much (other that deep pockets) really impacts the success in doing things others are not doing—or leading a group in doing things others are not leading that group.